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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers

Fig. 1

The experimental BBB model. Schematic for the in vitro BBB model of pBECs (porcine brain endothelial cells) in Non-Contact Co-culture (NCC) with astrocytes (a). Validation of the model with representative TEER (trans-endothelial cells resistance) values post NCC days (b). Representative micrographs of immunostainings for tight junction marker proteins showing (c) Claudin 5 (c) and ZO-1 (d). Scale bars show 15 µm

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