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Table 3 Correlations between cyst fluid concentrations of serum proteins and hormones

From: Glioblastoma microenvironment contains multiple hormonal and non-hormonal growth-stimulating factors

 

APOA1

Albumin

SHBG

(Mw 28)

(Mw 66)

(Mw ~ 100)

IGF-1

0.52b

0.34

0.47a

Insulin

0.16

− 0.03

0.13

Erythropoietin

− 0.07

− 0.28

− 0.20

Growth hormone

0.57b

0.54b

0.65c

Testosterone

0.20

0.45a

0.27

Estradiol

− 0.01

0.22

0.07

Triiodothyronine

0.48a

0.30

0.05

SHBG

0.56b

0.54b

 

Albumin

0.97c

  
  1. Cyst fluid from 25 patients with cystic glioblastomas were analyzed with respect to hormones and serum proteins, and MRIs were used to calculate the volumes of tumors and cysts. Correlations were calculated with Pearson’s test. Asterisks: ap < 0.05; bp < 0.01; cp < 0.001. Abbreviations: APOA1: apolipoprotein A–I; IGF-1: insulin-like growth factor 1; Mw: weight; SHBG: sex hormone-binding globulin