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Table 3 Correlations between cyst fluid concentrations of serum proteins and hormones

From: Glioblastoma microenvironment contains multiple hormonal and non-hormonal growth-stimulating factors

  APOA1 Albumin SHBG
(Mw 28) (Mw 66) (Mw ~ 100)
IGF-1 0.52b 0.34 0.47a
Insulin 0.16 − 0.03 0.13
Erythropoietin − 0.07 − 0.28 − 0.20
Growth hormone 0.57b 0.54b 0.65c
Testosterone 0.20 0.45a 0.27
Estradiol − 0.01 0.22 0.07
Triiodothyronine 0.48a 0.30 0.05
SHBG 0.56b 0.54b  
Albumin 0.97c   
  1. Cyst fluid from 25 patients with cystic glioblastomas were analyzed with respect to hormones and serum proteins, and MRIs were used to calculate the volumes of tumors and cysts. Correlations were calculated with Pearson’s test. Asterisks: ap < 0.05; bp < 0.01; cp < 0.001. Abbreviations: APOA1: apolipoprotein A–I; IGF-1: insulin-like growth factor 1; Mw: weight; SHBG: sex hormone-binding globulin