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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Vascular network expansion, integrity of blood–brain interfaces, and cerebrospinal fluid cytokine concentration during postnatal development in the normal and jaundiced rat

Fig. 2

Blood–brain and blood–CSF barrier integrity in normobilirubinemic and hyperbilirubinemic male and female rats during post-natal development. The integrity of the barriers was assessed by measuring their permeability toward [14C]-sucrose used as a polar tracer. A Apparent Kin brain measured in 8-h-old animals. B True Kin brain measured in 9-day-old animals. C Kin CSF measured in 8-h-old (P0) and 9-day-old (P9) animals. Data are expressed as means ± SEM, individual values are shown as open circles. Note that P0 and P9 tissue data are expressed as apparent and true Kin, respectively. See methods for permeability constant definition and calculation

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