Skip to main content

Table 1 Overview of mouse Cre lines for targeting ChP

From: Experimental approaches for manipulating choroid plexus epithelial cells

Mouse line Age of Cre onset Consequences References
FOXJ1-Cre Cre expression occurs in ciliated epithelial cells present in the ChP Gene deletion in all ChP [28, 49]
Cre expression occurs in ciliated epithelial cells present in the ChP Gene expression in all ChP [12, 38]
Nestin-Cre Around E10.5 [56]
Foxj1-CreERT2::GFP Tamoxifen-inducible at E13.5 and confirmed at E15.5 in the reference [66]
Pax2-Cre Confirmed at E12.5 in the reference Conditional gene deletion in 4 V ChP [19]
Wnt1-Cre Confirmed at E12.5 in the reference [50, 52]
Wnt1-Cre2 Confirmed at E12.5 in the reference [53]
Foxj1-CreERT2::GFP Tamoxifen-inducible E10.5-E12.5 and confirmed at E12.5 in the reference [53, 67]
Gdf7-Cre Confirmed at E12 in the reference [50, 68]
Otx2-CreERT2 Tamoxifen-inducible at E9 and, confirmed at E11 in the reference Conditional gene deletion in all ChP [68]
LPV-Cre.0607 Onset not specified, Adult expression in reference [54]
TAT-Cre delivery Adult (5 days after single injection) [71,72,73,74]