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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Arterial vasodilation drives convective fluid flow in the brain: a poroelastic model

Fig. 3

The asymmetric waveform of functional hyperemia can drive net directional fluid flow through the PVS. a The radially outward displacement (blue) and velocity (green) of the arteriolar wall for the case of symmetric dilation (top) and asymmetric dilation (bottom). b The time averaged radial Peclet numbers at the PVS-ECS interface as a result of symmetric (top) and (asymmetric) vasodilation. c The pressure and relative fluid velocity in the PVS and the ECS at the times of maximum radially outward and inward arteriolar wall velocity for symmetric (top) and asymmetric (bottom) dilation. The colors show the pressure value in mmHg and the arrows show the magnitude and direction of relative fluid flow. By comparing the ratio of the maximum relative velocity in the PVS and SAS, it can be seen with asymmetric vasodilation more fluid enters the ECS through the PVS than returns into the PVS through the ECS

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