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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Theoretical analysis of wake/sleep changes in brain solute transport suggests a flow of interstitial fluid

Fig. 1

Sketch of the effect of the wake-to-sleep increase in the volume of the interstitial space (blue shading) and the porosity on the diffusive and advective fluxes of a solute. Dilution of the solute with increasing porosity decreases the diffusive flux (left panels), but reduced hydraulic resistance with increasing porosity increases the flow velocity (right panels) and the advective flux

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