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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited

Fig. 6

Choroidal transport mechanisms implicated in CSF secretion. Polarized localization of select transporters in the choroid plexus epithelium. NBCe2, NCBE, AE2; bicarbonate transporters, AQP1; aquaporin 1, NKCC1; Na+/K+/2Cl− cotransporter 1, KCC; K+/Cl− cotransporter 1, NKA; Na+/K+-ATPase, K+ Ch; K+ channels. Figure adapted from [146]. The read lines indicate a K+ shuttle with a potential efflux across the basolateral membrane via KCC1 in situations of high ventricular [K+]o (dashed red line with small arrow head)

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