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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited

Fig. 1

The CSF-containing ventricular system and choroid plexus. A The fluid-filled ventricular system and subarachnoid space (grey) with choroid plexus marked in black. LV; lateral ventricle, TV; third ventricle, FV; fourth ventricle, SAS; subarachnoid space. Inset illustrates the monolayer of choroid plexus epithelial cells bordering on the vasculature (in red) with tight junctions illustrated as bars and AQP1 as light grey spheres on the luminal-facing side. B Scanning electron microcopy images of rat choroid plexus illustrates the frond-like arrangement of the epithelium dictated by the ensheathment of blood vessels in the underlying connective tissue and the abundant and interdigitated microvilli. Scale bars 500 μm (top panel), 50 μm (insert), 5 μm (bottom panel). SEM images courtesy of Frederik Vilhardt, University of Copenhagen

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