Fig. 4
From: Parasagittal dural space and cerebrospinal fluid (CSF) flow across the lifespan in healthy adults
Relationship of age with different anatomical characteristics for (A) cerebrospinal fluid (CSF), (B) gray matter (GM), (C) white matter (WM), (D) parasagittal dural (PSD) volumes, (E) retrograde flow, and (F) anterograde flow in the cerebral aqueduct. As expected, data show a significant correlation of GM and CSF volume with age. In addition, this study shows a novel significant relationship of normal aging with PSD volume, and CSF flow in the cerebral aqueduct. Non-significant trends appear in light gray shade; significant trends appear in dark gray shade. Gray area corresponds to 95 percent confidence intervals estimated using the Wald method. Relationships that do not reach the significant threshold after multiple comparison correction appear in light gray shade; significant relationships are denoted with an asterisk and with confidence intervals appearing in dark gray shade