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Table 2 Summary of baseline in vivo brain compartment volumes across CEP164fl/fl vs FOXJ1-Cre;CEP164fl/fl groups

From: Sustained glymphatic transport and impaired drainage to the nasal cavity observed in multiciliated cell ciliopathies with hydrocephalus

Dependent variable

CEP164fl/fl (N = 10)

FOXJ1-Cre; CEP164fl/fl (N = 10)

Difference

SE

p-value

L95%

U95%

Mean

SE

Mean

SE

Total intracranial volume, TIV (mm3)

478.1

5.3

512.6

11.5

− 34.5

12.6

0.018

− 61.9

− 7.9

Brain tissue volume (mm3)

468.3

4.7

471.8

6.2

− 3.5

7.7

0.656

− 19.8

12.8

Cerebral ventricle (CV) volume (mm3)

5.4

0.5

35.6

7.6

− 30.2

7.6

0.003

− 47.5

− 12.9

CV volume fraction of TIV (%)

1.1

0.1

6.7

1.2

− 5.6

1.2

0.001

− 8.4

− 2.9

Olfactory bulb volume (mm3)

20.3

0.6

13.8

0.6

6.6

0.8

< 0.001

4.9

8.2

  1. Data are presented as means and SE’s; Mean differences compare CEP164fl/fl and FOXJ1-Cre;CEP164fl/fl groups for each dependent variable. L95%: lower limit of 95% confidence interval for mean (CI), U95%: upper limit of 95% CI
  2. p-values marked with bold indicate that the mean difference is significant at the 0.05 level.