Table 1 Overview of experimental groups including mortality, MRI, age, and sex of animals included in analysis
Group | Strain | Mortality | Scan related issues | Age (weeks) | Sex, % Male | MRI morphometry | MRI glymphatics | ICP recording |
|---|---|---|---|---|---|---|---|---|
1 | CEP164fl/fl (N = 13) | N = 1 | N = 2 | 12.8 ± 0.5 | 56.0 | N = 10 | N = 7 | No |
2 | FOXJ1Cre; CEP164fl/fl (N = 14) | N = 3 | N = 1 | 13.3 ± 0.4 | 20.0 | N = 10 | N = 8 | No |
3 | p73+/+ (N = 8) | N = 0 | N = 0 | 19.9 ± 1.0 | 62.5 | N = 8 | N = 8 | No |
4 | p73−/− (N = 8) | N = 1 | N = 1 | 19.0 ± 1.0 | 85.7 | N = 7 | N = 6 | No |
5 | CEP164fl/fl (N = 9) | N = 2 | N/A | 22.6 ± 4.2 | 16.7 | No | No | Yes |
6 | FOXJ1Cre; CEP164fl/fl (N = 7) | N = 2 | N/A | 26.6 ± 6.4 | 60.0 | No | No | Yes |
7 | p73+/+ (N = 5) | N = 1 | N/A | 49.9 ± 9.3 | 66.7 | No | No | Yes |
8 | p73−/− (N = 6) | N = 0 | N/A | 34.5 ± 3.4 | 83.3 | No | No | Yes |