Fig. 5

AQP4 expression is increased in p73^−/− but not in FOXJ1-Cre;CEP164^fl/fl mice. A, B Representative fluorescent micrographs of AQP4 expression in ventral hippocampus of p73^+/+ mice and p73^−/− knockout mice. Image display settings are identical between micrographs in panels A and B. Subpanels of individual capillaries is magnification of dashed box in respective main image. C Mean polarization index of AQP4 around capillaries in ventral hippocampus was significantly increased in p73^−/− knockout mice relative to p73^+/+ mice (p = 0.048). D, E Representative fluorescent micrographs of AQP4 expression in ventral hippocampus of CEP164^fl/fl mice and FOXJ1-Cre;CEP164 ^fl/fl knockout mice. Image display settings are identical between micrographs in panels D and E. Subpanels of individual capillaries is magnification of the dashed box in respective main image. F Mean polarization index of AQP4 around capillaries in ventral hippocampus did not significantly differ between CEP164^fl/fl and FOXJ1-Cre;CEP164^fl/fl knockout mice (p = 0.186). Scale bars = 10 μm. Mean value of all capillaries within an individual animal is represented indicated by black circle in panels C and D. Groupwise bars with error = Mean ± SEM. *p < 0.050