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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter

Fig. 4

Correlation between the decrease of subventricular zone area and ventricular volume in the hydrocephalic pigs. A The increase of ventricular volumes correlated with the decrease of the SVZ area in the hydrocephalic pigs. B, C Hematoxylin–eosin staining showing the decrease of the SVZ area when the ventricular volume increased. The SVZ was divided in its two main areas, the abventricular SVZ (AVSZ) and ventricular SVZ (VSVZ) in D sham control pig and E hydrocephalic pig. F The AVSZ area decreased in the hydrocephalic pigs. Scale bars represent 300 µm in B, C; 250 µm in D, E. *p = 0.014, Wilcoxon–Mann–Whitney test. Simple linear regression with a R squared of 0.6065, p-value 0.03. Images were obtained under the bright microscope. lv lateral ventricle lumen

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