Cultured brain endothelial cells | Control | l-ornithine | |
---|---|---|---|
Number of images analyzed | 29 | 48 | |
Luminal membrane | Smooth | 74% | 67% |
Protrusions | 26% | 33% | |
Glycocalyx | Continuous | 89% | 29% |
Discontinuous | 11% | 71% | |
Tight junctions | Intact | 100% | 78% |
Discontinuous | 0% | 22% | |
Mitochondria | Intact | 97% | 53% |
Altered | 3% | 47% | |
Vesicular profiles / image | Luminal membrane | 5.9 ± 4.3 | 8.7 ± 4.5* |
Abluminal membrane | 2.2 ± 1.5 | 5.9 ± 3.8*** | |
Vesicular profiles ratio | Luminal membrane | 73% | 60% |
Abluminal membrane | 27% | 40% | |
Vacuolization | Present | 14% | 27% |