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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Blood–brain barrier dysfunction in l-ornithine induced acute pancreatitis in rats and the direct effect of l-ornithine on cultured brain endothelial cells

Fig. 3

Representative transmission electron micrographs of pancreas and brain from rats injected with saline (control) and animals with acute pancreatitis induced by l-ornithine (n = 4). The negatively charged surface glycocalyx was labeled with the cationic dye Alcian blue. A acinar cells, AB Alcian blue, BM basal membrane, ER endoplasmic reticulum, G glial endfeet, L vessel lumen, m mitochondria, n nucleus, P pericyte, TJ intercellular tight junction. Black arrows in the l-ornithine-treated pancreas group point to plasma membrane deformities on the luminal surface of endothelial cells. Stars in the l-ornithine-treated brain group label discontinuities of the luminal surface glycocalyx. Scale bars: 500 nm or 1 µm

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