Fig. 7

The effects of rCCL5 and SRC CRISPR (KO) on neurological outcomes and expression of CCR1 and its downstream signaling proteins in naïve mice. A Modified Garcia test. B Forelimb placement test. C Corner turn test. D Representative western blot bands. E–K Quantitative analyses of CCR1, p-SRC, Rac1, albumin, MMP9, claudin-5, occludin, and ZO-1 in the ipsilateral hemisphere 24 h post-ICH. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 vs. Naïve, ^#p < 0.05 ^##p < 0.01, ^###p < 0.001 vs. Naïve + vehicle. Data were expressed as mean ± SD. n = 6/group