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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Human in silico trials for parametric computational fluid dynamics investigation of cerebrospinal fluid drug delivery: impact of injection location, injection protocol, and physiology

Fig. 3

Overview of in vitro system and bench top experiment setup a 3D printed n-vitro model of the CSF system with placement of flash lightning and imaging camera. b CSF reservoir tank and custom ventricular oscillatory CSF flow pump in the ventricles. c Continuous injection pump for tracer injection at ICV, CM, and LP. d Oscillatory pump to induce CSF oscillations in the SAS to match the CSF flow field acquired by phase contrast-MRI

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Fluids and Barriers of the CNS

ISSN: 2045-8118