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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Human in silico trials for parametric computational fluid dynamics investigation of cerebrospinal fluid drug delivery: impact of injection location, injection protocol, and physiology

Fig. 1

Overview of numerical model based on subject specific MRI measurements. a Computational model of the entire CSF space for the human analyzed superimposed on a T2-weighted MR image used to acquire subject-specific anatomy and natural CSF oscillation. (a1) Magnification of cervical nerve roots (a2) Magnification of lumbar nerve roots (a3) Visualization of the needle surface mesh used for tracer injection. b Cranial SAS compartments consisting of ventricular system, cerebellum, basal cistern, and cortical subarachnoid space (left and right)

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Fluids and Barriers of the CNS

ISSN: 2045-8118