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Table 2 EB concentrations on cerebrospinal fluid with multiple stimulation strategy

From: Facilitating drug delivery in the central nervous system by opening the blood-cerebrospinal fluid barrier with a single low energy shockwave pulse

Multiple stimulation strategy Drug concentration in the CSF (%)
Locations Pulse(s) FSW Control  
C 1 0.39 ± 0.06 0.04 ± 0.04 **
C 10 5.58 ± 2.23   **
A-B-C 1 1.28 ± 0.53   **
CL-CR 1 1.73 ± 0.47   **
  1. **, p < 0.01 vs. control, in one-way ANOVA with the Tukey post hoc test (n = 5)
  2. Sampling time: at 3 h after the FSW-treatment
  3. Unit: %, CSF/blood Evans blue concentration