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Fig. 8 | Fluids and Barriers of the CNS

Fig. 8

From: Facilitating drug delivery in the central nervous system by opening the blood-cerebrospinal fluid barrier with a single low energy shockwave pulse

Fig. 8

a Experimental timeline for doxorubicin and FSW treatment. b Longitudinal brain tumor monitoring via luciferase activity using an IVIS, wherein the relative IVIS signal (%) is the IVIS signal intensity at the specified sampling day divided by the IVIS signal intensity 7 days after tumor cell implantation. **p and ##p < 0.05 vs. control and Sham, respectively, in one-way ANOVA with the Tukey post hoc test (n = 5). c Comparison of animal survival duration among the FSW group (FSW + DOX), Sham group, and control group (*p < 0.05 in one-way ANOVA with the Tukey post hoc test). In which, Control: GBM-rats without any treatment; Sham: GBM-rats with DOX treatment only; FSW: GBM-rats with FSW-DOX treatment (n = 5)

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Fluids and Barriers of the CNS

ISSN: 2045-8118