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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Facilitating drug delivery in the central nervous system by opening the blood-cerebrospinal fluid barrier with a single low energy shockwave pulse

Fig. 5

a Fluorescence images of different brain section levels at position C. The indicator was 70 kDa FITC-dextran. The sampling times was 24, 72 and 120 h after the FSW treatment. b Comparison of the average fluorescence flux across all sections using either 70 kDa or 500 kDa FITC-dextran as the indicator. The sampling times were 3, 24, 72, and 120 h after the FSW treatment at position C. #p and ξp < 0.05 vs. 24 h and 72 h, respectively, sum of all sections; in one-way ANOVA with the Tukey post hoc test (n = 5); **p and ##p < 0.01 vs. 3 h and 24 h, respectively, sum of all sections; in one-way ANOVA with the Tukey post hoc test (n = 5)

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