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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Facilitating drug delivery in the central nervous system by opening the blood-cerebrospinal fluid barrier with a single low energy shockwave pulse

Fig. 4

a Fluorescence images of each histological section from a rat after FSW treatment at different sites and from a control rat (no FSW treatment). The rats were injected with 70 kDa FITC-dextran as the indicator. The sampling time was 3 h after FSW treatment; b Quantitative results with 70 kDa FITC-dextran as the indicator for different brain sections following treatment at different sites. *p < 0.05 vs. other treatment positions, in the same section, in one-way ANOVA with the Tukey post hoc test (n = 5); c Total fluorescence intensity of (b) at different treatment sites. **p < 0.01 vs. other treatment positions, in one-way ANOVA with the Tukey post hoc test (n = 5); d Quantitative results with 500 kDa FITC-dextran as the indicator. *p < 0.05 vs. other treatment positions in the same section in one-way ANOVA with the Tukey post hoc test (n = 5); e Total fluorescence intensity of (d) at different treatment sites. *p < 0.05 vs. other treatment positions, in one-way ANOVA with the Tukey post hoc test (n = 5)

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Fluids and Barriers of the CNS

ISSN: 2045-8118