Fig. 5
No effect of astrocyte HIF-1 LoF on vascular characteristics. A Representative images of CD31-stained microvessels (green) in cortex, sub-cortex and hippocampus of GLAST-CreERT2;HIF-1αfl/fl mice treated with or without tamoxifen after 96 h normoxic or hypoxic exposure. Scale bar = 50 µm. Quantification of cortical mean vessel diameter (B), vessel number (C) and vessel density (D). Two-way ANOVA, mean ± SD, n = 3, *p < 0.05 compared to Nx Ctrl and Nx LoF