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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Pericyte, but not astrocyte, hypoxia inducible factor-1 (HIF-1) drives hypoxia-induced vascular permeability in vivo

Fig. 1

Generation of transgenic perivascular mouse lines. Schematic overview of the generation of transgenic mouse lines with conditional (CreERT2) astrocyte- (GFAP, GLAST) or pericyte-targeted (SMMHC) HIF-1 LoF. Excision of floxed HIF-1α exon 2 was induced by intraperitoneal injection of tamoxifen (50 mg/kg body weight) over 5 consecutive days followed by a 5 day recombination period

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Fluids and Barriers of the CNS

ISSN: 2045-8118