Biochemical profile of human infant cerebrospinal fluid in intraventricular hemorrhage and post-hemorrhagic hydrocephalus of prematurity

Table 3 Increased CSF Calcium and Magnesium in PHH but no difference in Bicarbonate compared to Control

		Control	LGIVH	HGIVH	PHH	P value
Magnesium	CSF	2.6 ± 0.6 (n = 13)	2.5 ± 0.3 (n = 6)	3.1 ± 0.6 (n = 6)	3.7 ± 0.8 (n = 4)	0.024 Control vs PHH (0.031); and LGIVH vs PHH (0.041)
Calcium	CSF	2.9 ± 0.7 (n = 15)	1.7 ± 0.8 (n = 7)	3.3 ± 0.9 (n = 7)	4.3 ± 0.3 (n = 4)	< 0.0001 Control vs LGIVH (0.013) and PHH (0.012); LGIVH vs HGIVH (0.0046) and PHH (< 0.0001)
	Serum	9.9 ± 0.5 (n = 9)	9.5 ± 0.6 (n = 5)	9.8 ± 0.4 (n = 6)	10.1 ± 0.3 (n = 5)	0.21
Bicarbonate	CSF	17.3 ± 4.3 (n = 13)	13.3 ± 2.3 (n = 7)	19.5 ± 2.3 (n = 6)	19.8 ± 1.0 (n = 4)	0.0062 LGIVH vs HGIVH (0.010) and PHH (0.019)
	Serum	24.9 ± 4.4 (n = 13)	25.1 ± 1.6 (n = 8)	24.3 ± 2.8 (n = 6)	25.9 ± 4.4 (n = 11)	0.85

Values recorded as mean ± standard deviation. In the “P value’ column, ANOVA summary p-value was recorded on the top row while significant pairwise post-test P value were recorded on the bottom row. All pairwise comparisons were analyzed based on Dunn’s or Tukey’s post-test ANOVA depending on the distribution of the data (normal distribution or not). n, represents sample size

ISSN: 2045-8118