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Table 2 Serum and CSF cellularity

From: Biochemical profile of human infant cerebrospinal fluid in intraventricular hemorrhage and post-hemorrhagic hydrocephalus of prematurity

 

Control (N = 18)

LGIVH (N = 10)

HGIVH (N = 13)

PHH (N = 11)

P value

CSF

     

 Total cells (cells/mcl)

1711 ± 4305

452.7 ± 596.1

12,572 ± 24,771

39,788 ± 70,835

0.014

Control vs PHH (0.012)

 Nucleated cells (cells/mcl)

3.8 ± 4.2

2.8 ± 3.2

67.2 ± 95.4

287.7 ± 433.2

Control vs HGIVH (0.0079) and PHH (0.0005); LGIVH vs HGIVH (0.011) and PHH (0.0010)

 Lymphocytes (%)

25.7 ± 16.3

23.0 ± 17.9

10.4 ± 4.5

17.1 ± 11.6

0.051

Control vs HGIVH (0.043)

 Neutrophils (%)

25.0 ± 11.7

30.0 ± 30.3

38.2 ± 32.4

49.4 ± 28.7

0.24

 Monocytes (%)

48.7 ± 22.9

46.6 ± 34.2

39.6 ± 32.6

16.3 ± 10.7

0.024

Control vs PHH (0.016)

 Macrophages (%)

10.2 ± 9.2

29.0 ± 25.2

28.3 ± 38.2

10.2 ± 6.1

0.23

Serum

     

 WBC (K/cumm)

12.1 ± 6.6

14.8 ± 9.9

15.0 ± 10.0

22.9 ± 10.0

0.051

Control vs PHH (0.042)

     

 RBC (K/cumm)

3.5 ± 0.7

3.7 ± 0.9

3.2 ± 0.6

3.5 ± 0.4

0.34

 Platelet (K/cumm)

329.6 ± 134.9

223.0 ± 66.6

202.9 ± 104.5

251.5 ± 92.2

0.032

Control vs HGIVH (0.030)

 Neutrophils (%)

47.5 ± 21.7

46.1 ± 25.1

42.2 ± 21.9

55.0 ± 13.4

0.53

 Lymphocytes (%)

40.7 ± 20.0

31.9 ± 18.6

36.5 ± 17.7

27.9 ± 11.8

0.37

 Monocytes (%)

8.3 ± 4.2

11.3 ± 4.5

9.5 ± 5.9

12.0 ± 5.4

0.18

  1. Values are reported as N (column %) or mean ± standard deviation. In the “P value’ column, ANOVA summary p-value was recorded on the top row while significant pairwise post-test P value were recorded on the bottom row. All pairwise comparisons were analyzed based on Dunn’s or Tukey’s post-test ANOVA depending on the distribution of the data (normal distribution or not). Cell differential reported as % of total WBC. WBC, white blood cells; RBC, red blood cells