Table 1 Summary of patient characteristics
|  | Control (N = 18) | LGIVH (N = 10) | HGIVH (N = 13) | PHH (N = 11) | P value |
|---|---|---|---|---|---|
Sex | |||||
 Male | 13 (72.2) | 6 (60.0) | 12 (92.3) | 9 (81.8) |  |
 Female | 5 (27.8) | 4 (40.0) | 1 (7.7) | 2 (18.2) |  |
PMA birth (weeks) | 31.1 ± 2.9 | 28.2 ± 2.8 | 26.2 ± 2.7 | 27.6 ± 3.1 | 0.0009 control vs HGIVH (0.0005) |
Birth Weight (g) | 1388.0 ± 395.5 | 1453.0 ± 752.8 | 986.2 ± 396.2 | 1041.1 ± 260.9 | 0.037 control vs HGIVH (0.032) |
CRIB II—T Score | 4.6 ± 4.5 | 6.9 ± 4.7 | 10.7 ± 3.9 | 8.7 ± 4.2 | 0.012 control vs HGIVH (0.0076) |
Complex Chronic Conditions | 0.8 ± 0.8 | 1.0 ± 0.7 | 0.8 ± 1.2 | 1.4 ± 1.1 | 0.39 |
 None | 9 (50.0) | 2 (20.0) | 7 (53.8) | 3 (27.3) |  |
 1–2 | 9 (50.0) | 8 (80.0) | 5 (38.5) | 6 (54.5) |  |
 3–4 | 0 | 0 | 1 (7.7) | 2 (18.2) |  |
  > 4 | 0 | 0 | 0 | 0 |  |
Respiratory | 6 | 4 (40.0) | 4 (30.8) | 7 (63.6) | Â |
Cardiovascular | 3 (16.7) | 0 | 2 (15.4) | 4 (36.4) | Â |
Neuromuscular | 2 (11.1) | 0 | 0 | 0 | Â |
Ophthalmologic | 1 (5.6) | 1 (10.0) | 1 (7.7) | 0 | Â |
Gastrointestinal | 0 | 0 | 2 (15.4) | 1 (9.1) | Â |
Infectious | 0 | 3 (30.0) | 0 | 0 | Â |
Hematologic | 1 (5.6) | 0 | 0 | 0 | Â |
NAS | 1 (5.6) | 2 (20.0) | 0 | 0 | Â |
FOR measurement | 0.35 ± 0.04 | 0.41 ± 0.07 | 0.49 ± 0.06 | 0.65 ± 0.03 |  < 0.0001 Control vs HGIVH (0.0003) and PHH (< 0.0001); LGIVH vs HGIVH (0.034) and PHH (< 0.0001); HGIVH vs PHH (< 0.0001) |