GO Term | Con vs MC58 | Con vs MC58siaD | Con + U0126 vs MC58 + U0126 | Con + U 0126 vs MC58siaD + U0126 | ||||
---|---|---|---|---|---|---|---|---|
p-value | Number annotated | p-value | Number Aannotated | p-value | Number annotated | p-value | Number annotated | |
Cellular response to lipopolysaccharide | 1.64 × 10–20 | 16 | 3.03 × 10–20 | 17 | 1.49 × 10–15 | 13 | 1.35 × 10–19 | 18 |
Cellular response to molecule of bacterial origin | 3.39 × 10–20 | 16 | 6.55 × 10–20 | 17 | 2.68 × 10–15 | 13 | 3.06 × 10–19 | 18 |
Cytokine-mediated signalling pathway | 4.08 × 10–20 | 22 | 2.22 × 10–21 | 25 | 5.17 × 10–12 | 16 | 6.30 × 10–19 | 26 |
Cellular response to interleukin-1 | 1.97 × 10–08 | 9 | 6.48 × 10–09 | 10 | 1.08 × 10–05 | 7 | 1.16 × 10–07 | 10 |
Regulation of NIK/NF-kappaB signalling | 4.63 × 10–05 | 6 | 2.26 × 10–04 | 6 |  |  | 1.21 × 10–03 | 6 |
NIK/NF-kappaB signalling | 5.84 × 10–04 | 6 | 2.78 × 10–03 | 6 |  |  |  |  |
Interleukin-6 production | 1.93 × 10–04 | 6 | 3.37 × 10–05 | 7 |  |  | 1.00 × 10–05 | 8 |
Negative regulation of interleukin-6 production | 9.11 × 10–04 | 4 | 2.68 × 10–03 | 4 | 4.99 × 10–04 | 4 | 8.35 × 10–03 | 4 |
Cell surface receptor signalling pathway | 1.82 × 10–10 | 25 | 7.24 × 10–12 | 30 | 1.73 × 10–06 | 20 | 3.69 × 10–09 | 32 |
Signal transduction by protein phosphorylation | 3.11 × 10–03 | 10 | 4.96 × 10–03 | 11 |  |  |  |  |
MAPK cascade | 2.85 × 10–03 | 10 | 4.51 × 10–03 | 11 |  |  |  |  |
Positive regulation of MAPK cascade | 3.93 × 10–03 | 8 | 2.99 × 10–03 | 9 |  |  |  |  |
Regulation of ERK1 and ERK2 cascade | 7.13 × 10–04 | 7 | 4.27 × 10–03 | 7 |  |  |  |  |
JAK-STAT cascade | 8.91 × 10–03 | 5 | 1.56 × 10–03 | 6 |  |  |  |  |
Negative regulation of cell death | 2.99 × 10–08 | 15 | 6.62 × 10–11 | 19 | 1.79 × 10–04 | 11 | 1.76 × 10–06 | 17 |
Response to tumour necrosis factor | 9.23 × 10–11 | 12 | 9.21 × 10–11 | 13 | 8.05 × 10–07 | 9 | 4.24 × 10–09 | 13 |
Regulation of tumour necrosis factor production | 3.14 × 10–04 | 6 | 5.93 × 10–05 | 7 |  |  | 7.86 × 10–03 | 6 |
Regulation of tumour necrosis factor superfamily cytokine production | 3.52 × 10–04 | 6 | 6.78 × 10–05 | 7 |  |  | 8.79 × 10–03 | 6 |