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Table 5 Validation of the MACE data by qPCR

From: Capsule-dependent impact of MAPK signalling on host cell invasion and immune response during infection of the choroid plexus epithelium by Neisseria meningitidis

 

qPCR

Stdev

MACE

FDR p-value

NFκβIZ

 Con vs. MC58

13.43

0.98

13.60

0.00

 Con + U0126 vs. MC58 + U0126

13.17

2.87

8.18

0.00

 Con vs. MC58siaD−

11.16

3.79

11.15

0.00

 Con + U0126 vs

MC58siaD− + U

11.99

4.21

8.80

0.00

Zc3H12A

 Con vs. MC58

11.98

2.54

11.63

0.00

 Con + U0126 vs. MC58 + U0126

11.28

2.91

12.04

0.00

 Con vs. MC58siaD−

11.81

2.83

10.14

0.00

 Con + U0126 vs

MC58siaD− + U

10.40

2.35

14.27

0.00

TNFα

 Con vs. MC58

14.35

2.89

18.47

0.00

 Con + U0126 vs. MC58 + U0126

17.08

1.72

18.21

0.00

 Con vs. MC58siaD−

15.36

2.55

17.79

0.00

 Con + U0126 vs

MC58siaD− + U

22.21

3.53

26.58

0.00

IL6

 Con vs. MC58

11.52

3.58

-

-

 Con + U0126 vs. MC58 + U0126

4.28

0.95

-

-

 Con vs. MC58siaD−

16.16

5.62

16.49

0.02

 Con + U0126 vs

MC58siaD− + U

7.73

3.32

8.56

0.02

IL8

 Con vs. MC58

18.21

8.86

14.03

0.00

 Con + U0126 vs. MC58 + U0126

30.36

8.88

16.17

0.00

 Con vs. MC58siaD−

19.51

6.04

14.45

0.00

 Con + U0126 vs

MC58siaD− + U

61.58

33.68

26.67

0.00

  1. The relative fold changes were determined using the 2−ΔΔCT method. The mean values and standard deviations (Stdev) of the qPCR data as well as the fold change of the DEG and the FDR p-values are shown