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Table 4 Summary of the DEG regulated by the NmB capsule-deficient mutant in presence and absence of the inhibitor U0126

From: Capsule-dependent impact of MAPK signalling on host cell invasion and immune response during infection of the choroid plexus epithelium by Neisseria meningitidis

Genesymbol

Genname

Fold change

  

con vs. MC58siaD−

con + U0126 vs. MC58siaD− + U0126

IL1B

Interleukin 1 beta

77.58

56.80

CCL20

C–C motif chemokine ligand 20

28.72

37.32

IL17C

INTERLEUKIN 17C

20.25

190.68

CXCL2

C-X-C motif chemokine ligand 2

19.03

26.60

TNF

Tumor necrosis factor

17.79

26.58

IL6

interleukin 6

16.49

8.56

CXCL1

C-X-C motif chemokine ligand 1

16.35

25.62

CSF2

colony stimulating factor 2

15.08

15.09

CXCL8

C-X-C motif chemokine ligand 8

14.45

26.67

CXCL3

C-X-C motif chemokine ligand 3

14.37

21.85

CCL2

C–C motif chemokine ligand 2

13.89

22.91

ANKRD37

Ankyrin repeat domain 37

 

12.78

IL1A

Interleukin 1 alpha

11.61

28.19

NFKBIZ

NFKB inhibitor zeta

11.15

8.80

TCIM

Transcriptional and immune response regulator

10.53

10.40

ZC3H12A

Zinc finger CCCH-type containing 12A

10.14

14.27

CXCL6

C-X-C motif chemokine ligand 6

9.75

13.31

IL4I1

Interleukin 4 induced 1

 

9.49

ICAM1

Intercellular adhesion molecule 1

9.46

11.60

RND1

Rho family GTPase 1

9.08

11.45

CXCL10

C-X-C motif chemokine ligand 10

 

8.81

CYP24A1

Cytochrome P450 family 24 subfamily A member 1

8.70

4.63

NOS2

Nitric oxide synthase 2

 

8.64

IL23A

Interleukin 23 subunit alpha

8.24

7.28

TNFAIP2

TNF alpha induced protein 2

7.81

8.00

SAA2

Serum amyloid A2

 

7.67

C6orf222

  

7.67

GFPT2

Glutamine-fructose-6-phosphate transaminase 2

 

7.60

PFKFB4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

 

7.43

NFKBIA

NFKB inhibitor alpha

7.34

9.29

ADM

Adrenomedullin

 

7.28

MIR210HG

MIR210 host gene

 

6.90

SPIB

Spi-B transcription factor

6.49

 

CHAC1

ChaC glutathione specific gamma-glutamylcyclotransferase 1

 

6.48

RASD1

Ras related dexamethasone induced 1

6.34

 

IGFBP1

Insulin like growth factor binding protein 1

6.27

 

ANKK1

Ankyrin repeat and kinase domain containing 1

 

5.99

LTB

Lymphotoxin beta

5.92

5.95

PTGS2

Lymphotoxin beta

5.68

4.50

G0S2

G0/G1 switch 2

 

5.46

ADORA2A

Adenosine A2a receptor

5.44

11.67

ZC3H12C

Zinc finger CCCH-type containing 12C

 

5.44

ANGPTL4

Angiopoietin like 4

5.34

10.50

LOC101929444

  

5.29

SOD2

Superoxide dismutase 2

5.21

7.17

LIF

LIF interleukin 6 family cytokine

5.01

 

SLC6A14

SOLUTE carrier family 6 member 14

4.97

6.04

TNFRSF11B

TNF receptor superfamily member 11b

 

4.90

CSF1

Colony stimulating factor 1

4.77

 

PI3

Peptidase inhibitor 3

4.73

4.62

SERPINA3

Serpin family A member 3

4.71

6.36

EGLN3

egl-9 family hypoxia inducible factor 3

 

4.70

IER3

Immediate early response 3

4.60

 

CX3CL1

C-X3-C motif chemokine ligand 1

4.59

8.78

PFKFB3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

 

4.59

RCAN1

Regulator of calcineurin 1

 

4.54

ZFP36

ZFP36 ring finger protein

4.48

 

CEBPD

CCAAT enhancer binding protein delta

4.47

4.97

TNFAIP3

TNF alpha induced protein 3

4.45

5.48

TNFRSF6B

TNF receptor superfamily member 6b

4.44

7.26

BHLHE40

Basic helix-loop-helix family member e40

 

4.38

HILPDA

Hypoxia inducible lipid droplet associated

4.27

4.99

PLAU

Plasminogen activator, urokinase

 

4.02

MAFF

MAF bZIP transcription factor F

4.13

 
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Fluids and Barriers of the CNS

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