Skip to main content

Table 3 Summary of the DEG regulated by the NmB wild type strain in presence and absence of the inhibitor U0126

From: Capsule-dependent impact of MAPK signalling on host cell invasion and immune response during infection of the choroid plexus epithelium by Neisseria meningitidis

Genesymbol

Genname

Fold change

con vs. MC58

con + U0126 vs. MC58 + U0126

IL1B

INTERLEUKIN 1 beta

64.65

 

CCL20

C–C motif chemokine ligand 20

23.85

20.68

IL17C

Interleukin 17C

22.48

79.66

CXCL2

C-X-C motif chemokine ligand 2

20.76

20.30

TNF

Tumor necrosis factor

18.47

18.21

CXCL1

C-X-C motif chemokine ligand 1

15.80

16.79

CXCL3

C-X-C motif chemokine ligand 3

14.48

15.66

CXCL8

C-X-C motif chemokine ligand 8

14.03

16.17

NFKBIZ

NFKB inhibitor zeta

13.60

8.18

CSF2

colony stimulating factor 2

13.01

 

CCL2

C–C motif chemokine ligand 2

12.47

11.80

IL1A

Interleukin 1 alpha

11.74

 

ZC3H12A

Zinc finger CCCH-type containing 12A

11.63

12.04

ANKRD37

Ankyrin repeat domain 37

 

10.05

TCIM

Transcriptional and immune response regulator

9.73

6.77

ICAM1

Intercellular adhesion molecule 1

9.68

7.98

RND1

Rho family GTPase 1

9.04

7.02

CXCL6

C-X-C motif chemokine ligand 6

7.92

7.67

CYP24A1

Cytochrome P450 family 24 subfamily A member 1

7,64

 

NFKBIA

NFKB inhibitor alpha

7.46

7.33

TNFAIP2

TNF alpha induced protein 2

7.24

5.59

IL23A

Interleukin 23 subunit alpha

6.10

 

LIF

LIF interleukin 6 family cytokine

5.97

 

PTGS2

Prostaglandin-endoperoxide synthase 2

5.89

 

ADORA2A

Adenosine A2a receptor

 

6.91

ADM

Adrenomedullin

 

6.36

PFKFB4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

 

6.34

ANGPTL4

Angiopoietin like 4

5.69

7.59

MIR210HG

MIR210 host gene

 

5.63

IL4I1

Interleukin 4 induced 1

 

5.48

CXCL10

C-X-C motif chemokine ligand 10

 

5.40

ZFP36

ZFP36 ring finger protein

5.19

 

C6orf222

 

4.98

5.77

CX3CL1

C-X3-C motif chemokine ligand 1

4.96

6.12

TNFAIP3

TNF alpha induced protein 3

4.94

5.03

FBXL8

F-box and leucine rich repeat protein 8

 

4.75

BHLHE40

Basic helix-loop-helix family member e40

 

4.36

IER3

IMMEDIATE early response 3

4.60

 

SLC6A14

Solute carrier family 6 member 14

4.59

 

LTB

Lymphotoxin beta

4.50

 

CEBPD

CCAAT enhancer binding protein delta

4.40

4.01

SOD2

Superoxide dismutase 2

4.30

4.09

MAFF

MAF bZIP transcription factor F

4.21

Â