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Table 2 Summary of the DEG regulated by the NmB wild type strain and capsule deficient mutant

From: Capsule-dependent impact of MAPK signalling on host cell invasion and immune response during infection of the choroid plexus epithelium by Neisseria meningitidis

Genesymbol

Genname

Fold change

  

con vs. MC58

con vs. MC58siaD−

IL1B

Interleukin 1 beta

64.65

77.58

CCL20

C–C motif chemokine ligand 20

23.85

28.72

IL17C

Interleukin 17C

22.48

20.25

CXCL2

C-X-C motif chemokine ligand 2

20.76

19.03

TNF

Tumor necrosis factor

18.47

17.79

IL6

Interleukin 6

0.00

16.49

CXCL1

C-X-C motif chemokine ligand 1

15.80

16.35

CXCL3

C-X-C motif chemokine ligand 3

14.48

14.37

CXCL8

C-X-C motif chemokine ligand 8

14.03

14.45

NFKBIZ

NFKB inhibitor zeta

13.60

11.15

CSF2

Colony stimulating factor 2

13.01

15.08

CCL2

C–C motif chemokine ligand 2

12.47

13.89

IL1A

Interleukin 1 alpha

11.74

11.61

ZC3H12A

Zinc finger CCCH-type containing 12A

11.63

10.14

TCIM

Transcriptional and immune response regulator

9.73

10.53

ICAM1

Intercellular adhesion molecule 1

9.68

9.46

RND1

Rho family GTPase 1

9.04

9.08

CXCL6

C-X-C motif chemokine ligand 6

7.92

9.75

CYP24A1

Cytochrome P450 family 24 subfamily A member 1

7.64

8.70

NFKBIA

NFKB inhibitor alpha

7.46

7.34

TNFAIP2

TNF alpha induced protein 2

7.24

7.81

SPIB

Spi-B transcription factor

 

6.49

RASD1

ras related dexamethasone induced 1

 

6.34

IGFBP1

Insulin like growth factor binding protein 1

 

6.27

IL23A

Interleukin 23 subunit alpha

6.10

8.24

LIF

LIF interleukin 6 family cytokine

5.97

5.01

PTGS2

Prostaglandin-endoperoxide synthase 2

5.89

5.68

ANGPTL4

Angiopoietin like 4

5.69

5.34

ADORA2A

Adenosine A2a receptor

 

5.44

ZFP36

ZFP36 ring finger protein

5.19

4.48

C6orf222

 

4.98

 

CX3CL1

C-X3-C motif chemokine ligand 1

4.96

4.59

TNFAIP3

TNF alpha induced protein 3

4.94

4.45

CSF1

Colony stimulating factor 1

 

4.77

PI3

Peptidase inhibitor 3

 

4.73

SERPINA3

Serpin family A member 3

 

4.71

IER3

Immediate early response 3

4.60

4.60

SLC6A14

Solute carrier family 6 member 14

4.59

4.97

LTB

Lymphotoxin beta

4.50

5.92

TNFRSF6B

TNF receptor superfamily member 6b

 

4.44

CEBPD

CCAAT enhancer binding protein delta

4.40

4.47

SOD2

superoxide dismutase 2

4.30

5.21

HILPDA

Hypoxia inducible lipid droplet associated

 

4.27

MAFF

MAF bZIP transcription factor F

4.21

4.13

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Fluids and Barriers of the CNS

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