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Table 1 Model baseline parameters

From: Interactions of brain, blood, and CSF: a novel mathematical model of cerebral edema

Component Description Value
\({V}_{A}\) Arterial-arteriolar volume 20 [ml]
\({V}_{C}\) Capillary volume 100 [ml]
\({V}_{V}\) Venous volume 30 [ml]
\({V}_{VEN}\) Ventricular volume 25 [ml]
\({V}_{BR}\) Brain volume 1400 [ml]
\({V}_{SAS}\) Subarachnoid space volume 35 [ml]
\({V}_{SPI}\) Spinal thecal sac volume 70 [ml]
\({V}_{TOT}\) Total cranial volume 1610 [ml]
\({P}_{AO}\) Aortic pressure 93 [mmHg]
\({P}_{ARL}\) Arteriolar pressure 64 [mmHg]
\({P}_{C}\) Capillary pressure 30 [mmHg]
\({P}_{V}\) Venous pressure 17 [mmHg]
\({P}_{SSS}\) Superior sagittal sinus pressure 7.4 [mmHg]
\({ICP}_{VEN}\) Ventricular pressure 10.8 [mmHg]
\({ICP}_{BR}\) Brain intraparenchymal pressure 10.5 [mmHg]
\({ICP}_{SAS}\) Subarachnoid space pressure 9.5 [mmHg]
\({P}_{SPI}\) Spinal thecal sac pressure 9.5 [mmHg]
\({Q}_{CSF}\) CSF production rate 0.0042 [ml\({\text{ sec}}^{ - 1}\)]
\(Q_{ISF}\) Interstitial fluid production rate 0.00083 [ml\({\text{ sec}}^{ - 1}\)]
\(Q_{CBF}\) Cerebral blood flow 910 [ml\({\text{ min}}^{ - 1}\)]
\(R_{A}\) Arterial-arteriolar resistance to flow 1.9 [mmHg s\({\text{ ml}}^{ - 1}\)]
\(R_{C}\) Capillary resistance to flow 2.5 [mmHg s\({\text{ ml}}^{ - 1}\)]
\(R_{V}\) Venous resistance to flow 0.8 [mmHg s\({\text{ ml}}^{ - 1}\)]
\(R_{BV}\) Bridging veins resistance to flow 0.7 [mmHg s\({\text{ ml}}^{ - 1}\)]
\(R_{BBB}\) Brain Blood Barrier 10,000,000 [mmHg s\({\text{ ml}}^{ - 1}\)]
\(R_{VEN}\) Ventricular resistance to CSF flow 250 [mmHg s\({\text{ ml}}^{ - 1}\)]
\(R_{BF}\) Resistance to bulk flow of cerebral interstitial flow 1200 [mmHg s\({\text{ ml}}^{ - 1}\)]
\(R_{OUT}\) Resistance to CSF reabsorption and bulk flow to the subarachnoid space 280 [mmHg s\({\text{ ml}}^{ - 1}\)]
\(R_{FM}\) Resistance to CSF flow through the Foramen magnum 15 [mmHg s \({\text{ml}}^{ - 1}\)]
\(C_{A}\) Arterial-arteriolar compliance 0.4 [ml\({\text{ mmHg}}^{ - 1}\)]
\(C_{C}\) Capillary compliance 5 [ml\({\text{ mmHg}}^{ - 1}\)]
\(C_{V}\) Venous compliance 5 [ml\({\text{ mmHg}}^{ - 1}\)]
\(C_{VEN}\) Ventricular compliance see Eq. 3
\(C_{BR}\) Brain compliance see Eq. 2
\(C_{SAS}\) Subarachnoid space compliance see Eq. 1
\(C_{SPI}\) Spinal thecal sac compliance see Eq. 5