Fig. 1

Graphical results of group comparisons and correlation analyses. Plots A-D illustrate comparisons of CSF cell count (A), CXCL13 levels (B), CXCR5+CD4 T cell numbers (C) and CXCR5+CD4 T cell frequencies (D) between ME (n = 29), NIMM (n = 22), and NIND (n = 6) subgroups. Association of CSF CXCL13 levels with CXCR5+CD4 T cell frequencies and the CSF/peripheral blood ratio of CXCR5+CD4 T cell frequencies of the total cohort (n = 57 and n = 49 respectively) are shown in plots E and F. ANOVA models were used for group comparisons (A, B) and Spearman’s Correlation Coefficient test for correlation analysis (E, F). Boxes visualize means with standard error of the mean (SE). Abbreviations: CSF, cerebrospinal fluid; ME, meningoencephalitis; NIMM, neuroimmunological disease; NIND, non-inflammatory neurological disease; PB, peripheral blood; * = p < 0.05; ** = p < 0.01