Skip to main content

Table 1 Demographics and frequencies of dichotomous imaging markers

From: Imaging features associated with idiopathic normal pressure hydrocephalus have high specificity even when comparing with vascular dementia and atypical parkinsonism

  iNPH, n = 55 VaD, n = 32 PSP, n = 30 MSA-P, n = 27 HC, n = 39 p-value
Age (years), median (range) 71 (56–86) 74 (60–84) 73 (61–84) 66 (45–80) 73 (58–84) 0.003a
Sex, male 29 (53) 21 (66) 15 (50) 12 (44) 15 (39) nsb
Focally enl. sulci 27 (49) 2 (6) 0 (0) 3 (11) 0 (0)  < 0.001b
Enl. Sylvian fissures 41 (75) 6 (19) 3 (10) 4 (15) 2 (5)  < 0.001b
DESH 35 (64) 4 (13) 2 (7) 0 (0) 0 (0)  < 0.001b
EI > 0.3 54 (98) 16 (50) 18 (60) 10 (37) 9 (23)  < 0.001b
  1. All data except age are n (%)
  2. iNPH, idiopathic normal pressure hydrocephalus; VaD, vascular dementia; PSP, progressive supranuclear palsy; MSA-P, multiple system atrophy parkinsonian type; HC, healthy controls; enl., enlarged; DESH, disproportionately enlarged subarachnoid-space hydrocephalus; EI, Evans’ index; ns, not significant
  3. aKruskal Wallis. Mann–Whitney was used as a post hoc test between each group and revealed that there was a significant difference in age between MSA-P and all other groups (iNPH vs MSA-P, p = 0.005)
  4. bχ2 test. All imaging markers were more frequent in iNPH than in the other groups