Table 2 Baseline characteristics of subjects with and without subsequent development of “iNPH” imaging changes
Parameter | No “iNPH” | Subsequent “iNPH” | Number of subjects | p-value |
|---|---|---|---|---|
Total (n) | 105 | 8 | 113 | Â |
Age (years, mean ± SD) | 64 ± 10 | 70 ± 3 | 113 | NS |
Sex (female/male, n) | 51/54 | 7/1 | 113 | NS |
Education (score, mean ± SD)a | 2.5 ± 1.0 | 2.0 ± 1.1 | 113 | NS |
Alcohol (daily units, mean ± SD) | 1.0 ± 0.9 | 1.3 ± 1.0 | 111 | NS |
Diabetes (y/n, n) | 11/93 | 3/5 | 112 | NS |
Hypertension (y/n, n) | 66/38 | 7/1 | 112 | NS |
Hypercholesterolaemia (y/n, n) | 78/26 | 7/1 | 112 | NS |
WMH (Fazekas score, mean ± SD) | 1.6 ± 1.2 | 2.9 ± 1.7 | 113 | 0.0255* |
SPPB (score, mean ± SD)b | 3.9 ± 0.3 | 3.6 ± 0.7 | 113 | NS |
TMT-B (sec, mean ± SD) | 103 ± 43 | 150 ± 60 | 113 | 0.0199* |
Walking speed (m/s, mean ± SD) | 0.4 ± 0.1 | 0.4 ± 0.1 | 113 | NS |
Executive function (z-score, mean ± SD) | 0.1 ± 0.6 | 0.1 ± 0.3 | 51 | NS |
g-factor (z-score, mean ± SD) | 0.1 ± 1.1 | 0.1 ± 0.8 | 51 | NS |
Memory (z-score, mean ± SD) | 0.1 ± 1.1 | 0.0 ± 0.9 | 54 | NS |
Visuopractical Skills (z-score, mean ± SD) | 0.0 ± 0.8 | 0.5 ± 0.8 | 54 | NS |