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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: SARS-CoV-2: is there neuroinvasion?

Fig. 6

Flow diagram showing possible effects of SARS-CoV-2 on the cerebrovasculature. CBF (cerebral blood flow), BBB (blood brain barrier), ACE2 (angiotensin converting enzyme 2), sACE2 (soluble ACE), IFN (interferon), CVS (cardiovascular centre), IL-1 (interleukin 1), TNFα (tumour necrosis factor α), CD147 (EMMPRIN (extracellular matrix metalloprotease inducer), ADAM17 (disintegrin and metalloprotease17), MMP9 (matrix metalloprotease 9), BP (blood pressure) and pO2 (partial pressure of oxygen)

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