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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Similarities and differences in the localization, trafficking, and function of P-glycoprotein in MDR1-EGFP-transduced rat versus human brain capillary endothelial cell lines

Fig. 4

Barrier integrity of monolayers of hCMEC/D3 and RBE4 wildtype and MDR1-EGFP expressing cells. Cells were grown on ThinCert® permeable membrane supports and barrier integrity was compared by measurement of transendothelial electrical resistance (TEER). TEER was measured daily over seven days after seeding using an EndOhm chamber. TEER values of 3–8 replicates are presented as means ± SEM. Statistical analysis performed by two-way ANOVA and Bonferroni post hoc test revealed no significant differences of TEER values between cell types

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Fluids and Barriers of the CNS

ISSN: 2045-8118