From: The regulatory roles of motile cilia in CSF circulation and hydrocephalus
Gene name | Average ciliary phenotype | Species | Defected ciliary motility | Hydrocephalus | References |
---|---|---|---|---|---|
Lrrc6 | Normal | Mice | Yes | Yes | [121] |
Hydin | Normal, stall | Mice | Yes | Yes | [122] |
Dnaaf1 | Normal | Mice | Yes | Yes | [123] |
Lrrc48 | Normal | Mice | Yes | Yes | [123] |
CFAP54 | Normal | Mice | Yes | Yes | [124] |
Mpdz | Normal | Mice | Yes | Yes | [125] |
Mdnah5 | Normal | Mice | Yes | Yes | [126] |
Zmynd10 | Normal | Mice | Yes | Yes | [127] |
Rsph9 | Ciliary membrane inclusions | Mice | Yes | Yes | [115] |
Ulk4 | Lesser | Mice | Yes | Yes | [87] |
Ccdc39 | Shorter | Mice | Yes | Yes | [113] |
Jhy | Shorter | Mice | Yes | Yes | [128] |
Snx27 | Shorter | Mice | Yes | Yes | [86] |
Ccdc40 | Shorter | Mice/zebrafish | Yes | Yes | [129] |
Dyx1c1 | Shorter | zebrafish | Yes | Yes | [130] |
Celsr 1 and celsr 2 | Shorter, and Lesser | Mice | Yes | Yes | [83] |
Dvls (Dvl1, 2 and 3) | Shorter, and Lesser | Mice | Yes | Yes | [114] |
MT1-MMP | Shorter, Lesser and Disorganized | Mice | Yes | yes | [131] |
Stumpy | Absent, severely deformed | Mice | Yes | Yes | [85] |
Pcdp1 | Â | Mice | Yes | Yes | [132] |
CFAP43 | Â | Mice | Yes | Yes | [133] |
Ccdc151 | Â | Mice | Yes | Yes | [134] |
Foxj1 | Shorter, and Lesser | Xenopus | Yes | Yes | (97) |