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Table 1 Demographic, clinical, and neuroimaging characteristics of CADASIL patients

From: Increased extracellular fluid is associated with white matter fiber degeneration in CADASIL: in vivo evidence from diffusion magnetic resonance imaging

  CADASIL (n = 38)
Age, mean (SD), y 49.7 (6.5)
Gender (female), n (%) 27 (71.1)
Duration of disease, median (IQR), y 2 (0.8—5)
Hypertension, n (%) 6 (15.8)
Diabetes mellitus, n (%)
Hyperlipidemia, n (%)
Smoking, n (%)
TIA/Stroke, n (%)
Headache, n (%)
Cognitive impairment, n (%)
Psychiatric impairment, n (%)
WMHs volume, mean (SD), ml
Corrected WMHs volume by ICV, mean (SD)
With lacunes, n (%)
With microbleeds, n (%)
3 (7.9)
3 (7.9)
3 (7.9)
18 (47.4)
22 (57.9)
14 (36.8)
17 (44.7)
81.1 (40.0)
0.057 (0.027)
27 (71.1)
21 (55.3)
  1. CADASIL Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, SD standard deviation, IQR interquartile range, TIA  transient ischemic attack, WMHs white matter hyperintensities, ICV intracranial volumes