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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Increased extracellular fluid is associated with white matter fiber degeneration in CADASIL: in vivo evidence from diffusion magnetic resonance imaging

Fig. 3

Correlations between FW, AFD with FW-corrected DTI metrics in WMHs. A, B FW correlated with AFD and MDt (both p < 0.001), and C, E AFD correlated with FAt, ADt and RDt (all p < 0.001). The MDt, ADt and RDt values are in units of × 10−3 mm2/s. *Indicates p < 0.0001. FW free water, AFD apparent fiber density, DTI diffusion tensor imaging, WMHs white matter hyperintensities, MDt tissue compartment mean diffusivity, Fat tissue compartment fractional anisotropy, ADt tissue compartment axial diffusivity, RDt tissue compartment radial diffusivity

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