Fig. 2

Abnormal diffusion metrics in WMHs: comparisons between WMHs and NAWM. Significant differences were found in all diffusion metrics including FW, AFD, FAt, MDt, ADt, RDt, FA, MD, AD and RD (all p < 0.001). The MDt, ADt, RDt, MD, AD and RD values are in units of × 10−3 mm2/s. WMHs = white matter hyperintensities; NAWM normal appearing white matter, FW free water, AFD apparent fiber density, FAt tissue compartment FA, MDt tissue compartment MD, ADt tissue compartment AD, RDt tissue compartment RD, FA  fractional anisotropy, MD mean diffusivity, AD axial diffusivity, RD radial diffusivity