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Table 6 Underexpressed biological processes related to glutathione metabolism

From: Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus

GO biological process Child category Number of genes process Number of genes underexpressed Expected value Fold enrichment P-value
Sulfur compound metabolic process (GO:0006790)   118 4 0.70 5.72 5.57E-03
  Glutathione metabolic process (GO:0006749) 35 2 0.21 9.64 1.87E-02
  1. Identification of biological processes related to underexpressed proteins in the white matter of hydrocephalic hyh mice compared with normal (wt) mice. PANTHER GO biological process complete annotation data set by application of a binomial test with Bonferroni correction for multiple testing with P < 0.05 was used. Gene ontology (GO) biological process terms are indicated. The expected value is the number of expected genes in the list for the category based on the reference list. A fold enrichment indicates that the category was overrepresented in hyh mice compared to wt mice