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Table 11 Functionally significant underexpressed and overexpressed proteins

From: Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus

Gene name Sum PEP Score Abundance Ratio: (Sample) / (Control) Abundance Ratio P-Value: (Sample) / (Control)
Aldehyde dehydrogenase family 1 member A3 9.87 3.63 ( >) 2.42E-07
Breast carcinoma-amplified sequence 1 homolog 79.33 0.51 ( <) 5.41E-06
Dynactin subunit 1 430.29 1.849 ( >) 1.44E-06
Dynactin subunit 4 108.84 1.58 ( >) 0.0003
Ermin 56.84 0.51 ( <) 0.0001
Galectin 1 21.94 1.61 ( >) 0.012
Gap junction gamma-3 protein 18.27 0.32 ( <) 9.09E-08
Gap junction alpha-1 protein 59.62 2.52 ( >) 1.20E-07
Gelsolin 178.38 0.72 ( <) 0.03
Neural cell adhesion molecule 1 542.26 1.62 ( >) 0.0001
Pleiotrophin 19.36 1.47 ( >) 0.03
  1. Functionally significant underexpressed ( < ) and overexpressed ( > ) proteins in the white matter of hyh mice related to oligodendrocyte differentiation and glial reactions that may be involved in hydrocephalus pathology. For meaning of sum PEP score and PSM see Table 2 legend