Fig. 2

Analysis of the elemental spectra using EDS-SEM. a, b Representative SEM images showing areas in wt (a) and hyh (b) mice selected to obtain spectra for quantification. The border between the grey (gm) and white (wm) matter is shown (white lines in a and b). c–e Atomic percentages of sodium (c, Na), chloride (d, Cl), and potassium (e, K) in the white and grey matter of wt (n = 3) and hyh mice (n = 3) indicating the presence of oedema. v lateral ventricle. *p < 0.05, **p < 0.005; ***p < 0.0005; Student’s t-test