Fig. 6
From: Brain pharmacokinetics of two BBB penetrating bispecific antibodies of different size
Capillary depletion for animals injected with [125I]mAb3D6-scFv8D3 (red) or [125I]di-scFv3D6-8D3 (blue). Values are expressed as percent of injected dose (%ID) for respective fraction and reported as mean ± standard deviation. The number of animals was 4 for each time point and antibody. A two-way analysis of variance followed by Bonferroni’s post hoc test was performed to compare %ID of capillary enriched fractions (**p < 0.01)