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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Reduction in pericyte coverage leads to blood–brain barrier dysfunction via endothelial transcytosis following chronic cerebral hypoperfusion

Fig. 2

Increased BBB permeability following CCH. a Left: schematic illustrating the injection of EB into the tail vein; right: gross anatomic changes in the Sham group and the 3 day group after EB injection. b Time-dependent change in the brain wet/dry weight ratio after operation. c Triple staining for COIV (red), ALB (green) and DAPI (blue) for assessment of ALB leakage in the CC. d, e Quantification of EB and ALB staining at different timepoints. n = 5 per group; NS, not significant; *p < 0.05, **p < 0.01 and ***p < 0.001 compared to the Sham group; one-way ANOVA followed by Dunnett’s post hoc test

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Fluids and Barriers of the CNS

ISSN: 2045-8118