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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: Neural crest cell-derived pericytes act as pro-angiogenic cells in human neocortex development and gliomas

Fig. 6

Radial glia/pericyte TNT relationships in the human developing cerebral cortex. a, b Triple staining with antibody NG2 2164C3, GFAP, and collagen IV reveals a very long pericyte TNT and the accompanying collagen IV basal lamina (a, arrows), enlarged on a single optical plane in b; note a TNT conveyed nucleus (arrowhead) and the extensive relations with GFAP+ radial glia fibers. c Multiple NG2+collagen IV+ TNTs (arrowheads) arise from the same parental vessel, one of which receives multiple contacts from a perivascular NG2+ OPC (arrow). d A ramified TNT arises from the pericyte body (arrowhead). Human telencephalon 22 weeks of gestation. Scale bars a 20 µm; bd 10 µm

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