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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Neural crest cell-derived pericytes act as pro-angiogenic cells in human neocortex development and gliomas

Fig. 3

Resting and migrating PCs. a An MMP2+ resting pericyte embedded in the collagen IV vessel basal lamina and b a migrating pericyte in the act of breaking out by releasing enzyme MMP2 (arrow). c, d Active PCs (arrow) passing through the collagen IV-enriched basal lamina; note the trace of the enzymatically attenuated collagen IV. Human telencephalon 18 weeks of gestation. A, astrocyte. Scale bars a, b 7.5 µm; c, d 15 µm

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