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Table 2 Changes in cerebrovascular flow dynamics from baseline (supine position) to HDT (n = 15 subjects)

From: Quantification of arterial, venous, and cerebrospinal fluid flow dynamics by magnetic resonance imaging under simulated micro-gravity conditions: a prospective cohort study

 

Arterial blood flow

Venous blood flow

CSF flow

Baseline ± SD

HDT ± SD

p-value

Baseline ± SD

HDT ± SD

p -value

Baseline ± SD

HDT ± SD

p-value

Average flow rate (mL/min)

867 ± 172

819 ± 177

−6 %

0.040*

−551 ± 214

−572 ± 157

+ 4 %

0.30

Systolic Peak flow rate (mL/min)

570 ± 108

522 ± 102

−8 %

0.040*

−474 ± 384

−576 ± 222

+ 22 %

0.24

−234 ± 84

−186 ± 66

−21 %

0.0088*

Diastolic Peak flow rate (mL/min)

444 ± 114

408 ± 90

−8 %

0.20

−498 ± 240

−492 ± 144

−1 %

0.93

138 ± 35

126 ± 52

−9 %

0.26

PtPPA (mL/min)

510 ± 126

450 ± 126

−12 %

0.020*

−456 ± 276

−486 ± 264

+ 7 %

0.24

372 ± 108

312 ± 102

−16 %

0.00098*

Flow volume/ cardiac cycle (mL/cardiac cycle)

15 ± 2.8

14 ± 3.4

−7 %

0.43

10 ± 4.6

10 ± 2.4

0 %

0.99

0.77 ± 0.20

0.68 ± 0.16

−12 %

0.10

CSA (mm2)

41 ± 7.6

43 ± 8.8

+ 5 %

0.32

82 ± 31

94 ± 40

+ 15 %

0.0050*

  1. Asterisks indicate statistical significance
  2. HDT, head-down tilt; CSF, cerebrospinal fluid; PtPPA, peak-to-peak pulse amplitude; CSA, cross-sectional area